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The U.S. National Library of Medicine provides a database of clinical trials worldwide. Use the fields below to search the database. Expand your results and select terms or phrases and right-click to search using Google, MalaCards, MedlinePlus, PubMed, or Wikipedia.

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Clinical Trials Search Results

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Count: 34
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NCT IDTitle
NCT04540965Impact of a Histamine H2 Receptor Antagonist (H2RA) on the Pharmacokinetics (PK) of Telaglenastat in Healthy Subjects
NCT04279769Study to Evaluate the Safety of CB-280 in Patients With Cystic Fibrosis
NCT02071862Study of the Glutaminase Inhibitor CB-839 in Solid Tumors
NCT03357627A Study of TAK-659 in Combination With Venetoclax for Adult Participants With Previously Treated Non-Hodgkin Lymphoma
NCT02071927Study of the Glutaminase Inhibitor CB-839 in Leukemia
NCT02771626Study CB-839 in Combination With Nivolumab in Patients With Melanoma, Clear Cell Renal Cell Carcinoma (ccRCC) and Non-Small Cell Lung Cancer (NSCLC)
NCT03263429Novel PET/CT Imaging Biomarkers of CB-839 in Combination With Panitumumab and Irinotecan in Patients With Metastatic and Refractory RAS Wildtype Colorectal Cancer
NCT02197572Effect of Sapanisertib (MLN0128) on the QTc Interval in Participants With Advanced Solid Tumors
NCT05275673A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer
NCT02049957Safety and Efficacy Study of Sapanisertib in Combination With Exemestane or Fulvestrant in Postmenopausal Women With Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative (ER+/HER2-) Metastatic Breast Cancer
NCT03163667CB-839 With Everolimus vs. Placebo With Everolimus in Participants With Renal Cell Carcinoma (RCC)
NCT04607512Study to Evaluate the ECG Effects of Telaglenastat in Healthy Adult Subjects
NCT02944435A Comparative, Pharmacokinetic Study of CB-839 Capsule and Tablet Formulations in Healthy Adults
NCT04698681NGS Screening Protocol to Detect Mutation of KEAP1 or NRF2/NFE2L2 Genes for the KEAPSAKE (CX-839-014) Trial
NCT03338881A Study to Assess Mass Balance, Pharmacokinetics (PK), and Metabolism of Orally Administered [14 C]-TAK-659 in Participants With Advanced Solid Tumor and/or Lymphoma Malignancies
NCT02000934A Study of TAK-659 in Adult Participants With Advanced Solid Tumor and Lymphoma Malignancies
NCT03428217CANTATA: CB-839 With Cabozantinib vs. Cabozantinib With Placebo in Patients With Metastatic Renal Cell Carcinoma
NCT03875313Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors
NCT02323113Safety, Tolerability, and Efficacy of TAK-659 in Adults With Relapsed or Refractory Acute Myelogenous Leukemia (AML)
NCT03370302A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of TAK-228 as Single Agent in Adult East Asian Participants With Advanced Nonhematological Malignancies
NCT02756364Sapanisertib in Combination With Fulvestrant in Women With Advanced or Metastatic Breast Cancer After Aromatase Inhibitor Therapy
NCT03359733A Study to Evaluate the Effect of Food on the Pharmacokinetics (PK) of TAK-659 in Participants With Advanced Solid Tumor
NCT04265534KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC
NCT03965845A Study of Telaglenastat (CB-839) in Combination With Palbociclib in Patients With Solid Tumors
NCT02834247A Study of TAK-659 in Combination With Nivolumab in Participants With Advanced Solid Tumors
NCT03057600Study of CB-839 in Combination w/ Paclitaxel in Participants of African Ancestry and Non-African Ancestry With Advanced Triple Negative Breast Cancer (TNBC)
NCT04824937Telaglenastat + Talazoparib In Prostate Cancer
NCT03772288A Study of TAK-659 in Combination With NKTR-214 in Participants With Advanced Non-Hodgkin Lymphoma (NHL)
NCT02071888Study of the Glutaminase Inhibitor CB-839 in Hematological Tumors
NCT03097328Study of TAK-228 In Patients With Previously Treated Metastatic Renal Cell Carcinoma
NCT03123393TAK-659 in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
NCT05319028Study of Mivavotinib (CB-659) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
NCT05521997Glutaminase Inhibition and Chemoradiation in Advanced Cervical Cancer
NCT03238651A Study of TAK-659 as a Single Agent in Adult East Asian Participants With Non-Hodgkin Lymphoma (NHL)