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The U.S. National Library of Medicine provides a database of clinical trials worldwide. Use the fields below to search the database. Expand your results and select terms or phrases and right-click to search using Google, MalaCards, MedlinePlus, PubMed, or Wikipedia.

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Clinical Trials Search Results

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NCT IDTitle
NCT05123820Pharmacokinetics of Omeprazole and Midazolam When Co-administered With ACT-1014-6470
NCT05597020A Post Approval Study to Investigate the Efficacy of Daridorexant in Subjects With Insomnia and Comorbid Nocturia
NCT04162366A Research Study to Show Aprocitentan is Efficacious and Safe to Treat Patients With Uncontrolled Blood Pressure and Chronic Kidney Disease.
NCT05549531A Study to Investigate the Effect of Itraconazole on the Way the Body Absorbs, Distributes, and Gets Rid of ACT-1004-1239 Given as a Single Dose of 10 mg to Healthy Male Subjects
NCT03239691A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients
NCT03100591A Study to Evaluate ACT-132577 in Healthy Male Subjects
NCT02708004Clinical Study to Assess Body Fluid Homeostasis After Administration of ACT-132577 in Healthy Subjects
NCT02479204Clinical Study to Investigate Safety and Effects on Heart Rate, Blood Pressure, and Pharmacokinetic Interactions of ACT-334441
NCT02099201Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-389949 in Healthy Subjects
NCT03545191Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects With Insomnia Disorder
NCT03765294A Study to Investigate the Effects of ACT-541468 on Nighttime Respiratory Function in Patients With Mild to Moderate Obstructive Sleep Apnea
NCT00458276Study of the Efficacy and Safety of Tezosentan in Patients With Pre-operative Pulmonary Hypertension, Due to Left Heart Disease, Undergoing Open Heart Surgery
NCT05672576A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus
NCT04052360Single Oral Dose of 4 mg Cenerimod in Healthy Japanese and Caucasian Subjects
NCT01877629Clinical Study to Assess the Pharmacokinetics, Safety, and Tolerability of ACT-129968 in Healthy Subjects
NCT03101189A Study of ACT-541468 in Healthy Japanese and Caucasian Subjects
NCT01094067Tezosentan in Patients With Pulmonary Arterial Hypertension
NCT04557280A Comparative Study of Selatogrel (ACT-246475) Formulations in Healthy Subjects
NCT05422612Department of Defense PTSD Adaptive Platform Trial - Master Protocol
NCT03657446A Study in Healthy Subjects to Investigate Whether Administration of Clazosentan Can Affect Normal Heart Function
NCT03596294A Study in Healthy Male Subjects to Investigate Whether Administration of Rifampicin Can Affect the Fate of Clazosentan in the Body of Clazosentan
NCT03372629A Study to Evaluate if ID-085 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects
NCT01264692Essential Hypertension
NCT03245229A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-132577 Can Affect Rosuvastatin's Fate in the Body (Amount and Time of Presence in the Blood)
NCT01954589Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206
NCT03869320A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male Subjects
NCT03384966A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease
NCT03541174A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety
NCT02702648First-in-man Study of Single and Multiple Ascending Doses of a New Drug for Neurological Disorders
NCT05254548A Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on What the Body Does to Flurbiprofen, Omeprazole, Midazolam in Healthy Subjects
NCT03575104Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep
NCT06393504Database Study to Provide Information on Pregnancy and Infant Outcomes Among Women Exposed to QUVIVIQ (Daridorexant)
NCT05948540Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant
NCT01241214Study of ACT-129968 in Adult Patients With Seasonal Allergic Rhinitis
NCT03425539Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease
NCT04183686A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects
NCT05877222A Phase 1 Trial to Investigate the Biological Equivalence of 5 × 10 mg Tablets and 2 × 25 mg Tablets of Daridorexant in Healthy Male and Female Japanese Participants
NCT03380455Effect of Cimetidine on the Pharmacokinetics of Lucerastat in Healthy Subjects
NCT03737214A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease
NCT02914223A Study to Evaluate Cenerimod in Healthy Male Subjects
NCT02571855A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects
NCT04252495The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics
NCT03657355Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug Users
NCT02472795Clinical Study to Investigate the Biological Activity, Safety, Tolerability, and Pharmacokinetics of ACT-334441 in Subjects With Systemic Lupus Erythematosus
NCT03017495A Clinical Study to Investigate the Potential Interactions Between Food and ACT-541468 and Between ACT-541468 and Midazolam
NCT05948579Department of Defense PTSD Adaptive Platform Trial - Intervention B - Vilazodone
NCT04286750Study in Healthy Subjects to Examine the Safety and Tolerability of ACT-1004-1239 Given as Multiple, Gradually Increasing Doses and to Examine the Effects of ACT-1004-1239 on the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-1004-1239
NCT02930655A Study to Assess the Safety and Tolerability of Lucerastat in Subjects With Fabry Disease
NCT03688555A Study to Evaluate the Effect of ACT-774312 in Subjects With Bilateral Nasal Polyposis
NCT00940095Clazosentan in Aneurysmal Subarachnoid Hemorrhage