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The U.S. National Library of Medicine provides a database of clinical trials worldwide. Use the fields below to search the database. Expand your results and select terms or phrases and right-click to search using Google, MalaCards, MedlinePlus, PubMed, or Wikipedia.

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Clinical Trials Search Results

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Count: 31
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NCT IDTitle
NCT04725240Open-Label Study of Setmelanotide in Hypothalamic Obesity
NCT02896192Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity
NCT03287960Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity
NCT06046443A Study to Assess Efficacy and Safety of LB54640 in Patients With Hypothalamic Obesity
NCT04963231DAYBREAK: A Study of Setmelanotide in Participants With Specific Gene Variants in the Melanocortin-4 Receptor (MC4R) Pathway
NCT02311673Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome
NCT03651765Long Term Extension Trial of Setmelanotide
NCT02041195Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients
NCT06239064Early Genetic Identification of Obesity
NCT05183802An Expanded Access Protocol for Setmelanotide for Treatment of Bardet-Biedl Syndrome (BBS)
NCT03013543Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity
NCT03262610Setmelanotide in a Single Patient With Partial Lipodystrophy
NCT06760546A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
NCT05093634EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway
NCT06239116A Study of RM-718 in Healthy Subjects and in Patients With HO
NCT04966741Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity
NCT02431442Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RM-493 Administered to Healthy, Obese, Non-diabetic Volunteers
NCT04348175A Phase 1 Study to Evaluate the Pharmacokinetics of Setmelanotide in Subjects With Varying Degrees of Renal Impairment
NCT06596135Open-Label Extension Study of Setmelanotide
NCT03479437The TEMPO (Tracing the Effect of the MC4 Pathway in Obesity) Registry
NCT05194124Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Participants With Specific Gene Defects in the MC4R Pathway
NCT01867437Effects of RM-493 on Energy Expenditure in Obese Individuals
NCT06420622INDIcators for Clarifying the bAckground of exTreme Obesity in childRen
NCT03746522Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity
NCT05774756A Trial of Setmelanotide in Acquired Hypothalamic Obesity
NCT03621007An Observational,Prospective Natural History Study of Early-Onset Extreme Obesity Due to Bi-Allelic Loss-of-Function Mutations in the POMC, PCSK1 or LEPR Genes
NCT01749137Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants
NCT05046132Study of Setmelanotide Effects on QTc (Corrected QT) Interval in Healthy Participants
NCT01849705Melanocortin 4 Receptor Mutations and Obesity-associated Diseases
NCT02849977Genetic Testing and Phenotypic Characterization of Severely Obese Pediatric and Adult Volunteers
NCT06772597A Single-center Study of Setmelanotide in Patients With Prader-Willi Syndrome